Toledo is a relatively large city which is generally best navigated by car.  Rental cars can be obtained upon arrival at the local airport.  For additional information, see http://www.tripadvisor.com/Travel-g51... .   The main interstate for Toledo drivers to know is Interstate 75.  The main street to know for internal travel in Toledo is West Bancroft.  Driving directions for almost any Toledo location can be located at www.maps.google.com.  A general driving map is available at http://www.toledo.com/maps/index.php.

Travelers interested in getting around Toledo without the use of a rental car will find that public transportation is a viable option.  The system in Toledo is comprised of a limited service trolley and a citywide bus system, each of which is inexpensive and easy to use.  Additional information about both of these systems can be obtained at http://www.tripadvisor.com/Travel-g51... .

For getting around Downtown Toledo, either the trolley or walking would be the best option.   Walking allows visitors to take their time seeing all that there is to see downtown and is widely preferred by people who have the time and leisure to use this method of getting around.   There are guided walking tours offered by the university for visitors who are interested.   More information is online at http://uac.utoledo.edu/UAC-Calendar/u... .